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Mechanical circulatory support : a companion to Braunwald’s heart disease
- ISBN: 9780323566995
- ISBN: 0323566995
- Call Number : WG 169.5 M486 2020
- Title: Mechanical circulatory support : a companion to Braunwald’s heart disease / [edited by] James K. Kirklin, Joseph G. Rogers.
- Edition: Second edition.
- Publication, Distribution: Philadelphia, PA : Elsevier, 2020.
- Physical Description: xvi, 298 p.: illustrations; 29 cm
- Notes: A companion to: Braunwald’s heart disease / edited by Douglas P. Zipes, Peter Libby, Robert O. Bonow, Douglas L. Mann, Gordon F. Tomaselli ; founding editor and online editor Eugene Braunwald. 11th ed. 2019
- Notes: "Expert consult."
- Notes: Includes bibliographical references and index
- Subject: Heart-Assist Devices.
- Subject: Heart Failure -- surgery.
- Subject: Heart Failure -- therapy.
- Added Entry: Kirklin, James K editor.
- Added Entry: Rogers, Joseph G editor.
- Added Entry: Braunwald’s heart disease Supplement to (work) 11th ed
- Added Entry: Mechanical circulatory support (Kormos)
- Cover
- Inside Front cover
- Copyright
- Dedication
- Contributors
- Preface
- Braunwald’s Heart Disease Family of Books
- Chapter 1: Historical Aspects of Mechanical Circulatory Support
- Chapter 2: Advanced Heart Failure and Cardiogenic Shock
- Chapter 3: Risk Stratification in Advanced Heart Failure
- Introduction
- Acute versus chronic heart failure
- Heart failure with preserved ejection fraction
- Sudden cardiac death versus progressive heart failure
- Elderly versus transplant referral populations
- Renal dysfunction
- Biomarkers
- Physical capacity and mortality risk in heart failure
- Exercise hemodynamics
- Frailty
- Multivariable risk stratification in heart failure
- Conclusion
- References
- Chapter 4: Candidate Selection and Decision Making in Mechanical Circulatory Support
- Introduction
- Indications for mechanical circulatory support
- Contraindications to MCS—medical, cardiac
- Right Ventricular Dysfunction
- Ventricular Arrhythmia
- Cardiac Anatomy, Prior Surgery, and Valve Disease
- Contraindications to MCS—Medical, Noncardiac
- Hematologic, Gastrointestinal, and Anticoagulation Considerations
- Renal Dysfunction
- Pulmonary Disease
- Peripheral Vascular Disease
- Cancer
- Infection
- Diabetes
- Malnutrition and Obesity
- Neurologic Disease
- Frailty
- Contraindications to MCS—nonmedical
- Temporary support to assess candidacy
- Formal evaluation protocols
- Shared decision making
- Summary
- References
- Chapter 5: Acute Circulatory Support
- Introduction
- The spectrum of cardiogenic shock
- Short-term mechanical circulatory support devices
- Complication of temporary circulatory support
- Clinical outcomes in shock patients supported with short-term mechanical circulatory support
- Conclusions/summary
- Disclosures
- References
- Chapter 6: The Role of Extracorporeal Membrane Oxygenation in Cardiac Support
- Chapter 7: Understanding the Principles of Continuous-Flow Rotary Left Ventricular Assist Devices
- Introduction
- Historical perspective
- General pump design
- CF rotary pump design: axial versus centrifugal pumps
- Bearing design/impeller suspension
- Hydrodynamic performance of CF pumps
- Interaction of the CF rotary pump and native heart
- Parallel and series circulation
- Flow estimation
- Limitations in flow control with cf rotary pumps
- Conclusion
- References
- Chapter 8: Hemocompatibility in Mechanical Circulatory Support
- Chapter 9: The Biological Response to Ventricular Unloading
- Introduction
- Cardiac hypertrophy-atrophy
- Contractile dysfunction, calcium handling, and cytoskeletal proteins
- Cardiac metabolism and bioenergetics
- Cell death and stress
- Natriuretic peptides and neurohormones
- Inflammatory markers
- Extracellular matrix and fibrosis
- Gene expression, rna, and proteomic profiling
- Endothelium and vasculature
- Studies on angiogenesis
- Future directions
- Summary
- References
- Chapter 10: Current Types of Devices for Durable Mechanical Circulatory Support
- Chapter 11: Operative Techniques and Intraoperative Management
- Historical note
- Principles of device selection
- Preoperative assessment and preparation
- Implant operation
- Intraoperative considerations
- Postoperative care
- References
- Chapter 12: Postoperative VAD Management: Operating Room to Discharge and Beyond
- Surgical and Medical Considerations
- Perioperative management
- Considerations in the operating room relevant to subsequent ICU care
- Early postimplantation ICU care
- Early postimplantation medical management in the ICU
- Pharmacologic management in the ICU
- Preparing for home discharge
- Standard outpatient visit
- References
- Chapter 13: Adverse Events and Mitigation Strategies
- Introduction
- Definitions
- Time-related occurrence, contributing factors, and causation
- Adverse event burden and era effect
- Adverse events contributing to death
- Perioperative bleeding
- Surgical wound infections
- Pump-related infection
- Gastrointestinal bleeding
- Neurologic dysfunction
- Renal failure
- Device failure
- Pump thrombosis
- Other thromboembolic events
- Aortic Insufficiency
- References
- Chapter 14: Right Heart Failure in Patients With Mechanical Circulatory Support
- Introduction
- Physiology and anatomy of the right ventricle
- Right ventricular failure in patients with chronic heart failure after lvad
- Right venticular afterload sensitivity and adaptation
- Preoperative evaluation and predictive risk scores
- Pulmonary artery pulsatility index
- Perioperative management of right ventricular function
- Mechanical circulatory support for right ventricular dysfunction
- Delayed right ventricular failure
- References
- Chapter 15: Clinical Trial Results in Mechanical Circulatory Support
- Chapter 16: Psychosocial and Quality of Life Issues in Mechanical Circulatory Support
- Preimplantation considerations
- Psychosocial outcomes during mechanical circulatory support
- Psychosocial predictors of clinical outcomes during mechanical circulatory support
- Postimplantation and end-of-life considerations
- Conclusions and future clinical and research directions
- References
- Chapter 17: Left Ventricular Assist Device in Special Population of Patients
- Chapter 18: Mechanical Circulatory Support in Pediatrics
- Chapter 19: Facilitating Myocardial Recovery
- History of recovery and device explantation
- Possible explanations of the low rate of myocardial recovery
- Optimizing myocardial recovery
- Harefield protocol
- Surgery for myocardial recovery
- Quality of life after left ventricular assist device explantation
- Summary and next steps to enhance rate of recovery
- References
- Chapter 20: The Critical Role of MCS Registries
- Chapter 21: Regulatory and Reimbursement Landscape for Mechanical Circulatory Support
- Introduction
- History of medical device regulations
- Global reimbursement
- Regulatory pathways for mechanical circulatory support devices
- Reimbursement pathways for mechanical circulatory support devices
- Mechanical circulatory support device total product life cycle
- Creating reimbursement for left ventricular assist devices
- Postmarket studies/surveillance
- Device tracking
- Mechanical circulatory support device registries
- Mechanical circulatory support device corrections and removals (recalls)
- Obsolescence
- Lessons learned
- Conclusions
- References
- Chapter 22: The Future of Mechanical Circulatory Support
- I. The trail blazed and the pathway ahead
- II. The future is leveraging the past
- III. The future is optimizing the present
- RECOGNIZING the OPPORTUNITIES
- MAPPING the Pathway to OPTIMIZATION
- OPTIMIZING TECHNOLOGY
- Optimizing Management
- OPTIMIZING PATIENTS
- IV. The future requires organization
- V. The future is now
- References
- Index
- Inside Back Cover